In the last part of the course, we discuss other subjects:
1) transcription factors and regulatory pathways and circuitry;
2) RNA transport to the cytoplasm and subcellular localization;
3) mechanisms to regulate RNA stability and translation (siRNA, miRNA & RNA binding proteins);
4) regulation of alternave splicing and alternative splicing effects and significance.

Therefore, you can search for papers to discuss also within these subjects and other that you may consider pertinent. There are also many subjects that are just "complementary" to the core lectures on chromatin and genome regulation and, as such, really OK to discuss.

Possible subjects may concern:
1) Regulatory pathways leading to gene expression changes or/and transcription factor binding to genome or/and general changes in chromatin behavior.
2) new DNA-binding proteins and new modalities of gene regulation;
5) alternative splicing in development or in diseases;
6) studies on miRNA function in development and disease;
7) endogenous siRNA, piRNA and other small RNA;
8) application of siRNA and miRNA technologies;
9) control of genome-wide gene expression in diseases and development, methods and applications.
10) any other that you may judge connected to the main course subjects.
Last modified: Friday, 25 July 2014, 5:45 PM