Weekly outline

• General

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  "Ce qui est simple est faux,
  ce qui est compliqué est inutile"
  Paul Valéry
  

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    About Moodle Page
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  • Advanced Cell Biology Module
    

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    General informations Page
  • Starting from October 11, appointment with G. Gambarotta: each monday, 2-4pm, Morphological Lab,
    
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    Forum of the cell biology lectures
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    Archives of 2011 pdf lectures Folder
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    Archives of 2011 audio podcasts of the lectures Folder
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    Bibliography Folder
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    Molecular Biology Module - Genomic Molecular Biology
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    Silver papers ! Page
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    Student's talk - Molecular Biology - Final Schedule Wiki
  • Please find thesis proposals at the Campusnet website
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    SPECIALE STUDENTI SANUM - modulo Biologia Molecolare del corso di GBFM
    Istruzioni e tabella articoli per presentazioni
    
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    Example articles for presentation File
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    Subject index File
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    Descrizione attività ed esami File

• 4 October - 10 October

  Introductory lectures
  

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    01 Lecture 04/10/10 Folder
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    02 Lecture 06/10/10 Folder
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    03 Lecture 08/10/10 Folder
  • i-care activities (Optional - Tutor G. Gambarotta)
    

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    Task 1: understanding immunoprecipitation Assignment
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    Task 2: understanding co-immunoprecipitation Assignment
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    Task 3: Cell count exercise (password = task 3) Quiz

• 11 October - 17 October

  Signal transduction and scaffold proteins Tutor will meet students on Monday October 11th , Morphological lab, 2-4pm

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    04 lecture 11/10/10 Folder
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    05 lecture 13/10/10 Folder
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    06 lecture 15/10/10 Folder
  • I-Care Activities

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    Task 4: protein-protein interaction Assignment
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    Task 5: How to produce polyclonal antibodies? Assignment
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    Task 6: How to produce monoclonal antibodies? Assignment
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    Survey

• 18 October - 24 October

  Cytoplasmic-Nuclear shuttling Tutor will meet students on Monday October 18th , Morphological lab, 2-4pm

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    07 Lecture 18/10/10 Folder
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    08 Lecture 20/10/10 Folder
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    09 Lecture 22/10/10 Folder
  • I-Care Activities

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    Task 07: Cos cells (password: i-care) Quiz
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    Task 08: understanding immunoprecipitation experiment (password: i-care) Quiz

• 25 October - 31 October

  Stem Cells - Biosafety and biosecurity Tutor will meet students on Monday October 25th, (aula da determinare) 2-4pm

  
  
  

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    10_lecture 25/10/10 Folder
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    11_lecture 27/10/10 Folder
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    12_lecture 29/10/10 Folder
  • I-Care Activities

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    Task 09: Where is the mistake.... Assignment
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    Task 10 what about antigens? Assignment

• 1 November - 7 November

  Autophagy (BCM)
  

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    13_lecture 03/11/10 Folder
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    14_lecture 05/11/10 Folder
  • I-Care Activities

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    Task 11: cell signaling complexity (no deadline-no post: just do it! Page
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    Task 12: RNAi principle and critical view of the technique Assignment

• 8 November - 14 November

  Cell migration - Ubiquitination (BCM) Tutor will meet students on Monday november 15th , Morphological lab, 2-4pm

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    15_lecture 08/11/10 Folder
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    16_lecture 10/11/10 Folder
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    dictyostelium URL
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    dictyostelium Page
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    17_lecture 12/11/10 Folder
  • I-Care Activities

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    consider Ubiquitin structure Jmol
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    Quiz- la struttura dell'Ubiquitina

• 15 November - 21 November

  Ubiquitin - attractive/repulsive clues Tutor will meet students on Monday november 22th , Morphological lab, 2-4pm

  
  

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    18_lecture 15/11/10 Folder
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    19_lecture 17/11/10 Folder
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    20_lecture 19/11/10 Folder
  • I-Care Activities

  • tasks have been reopened: deadline 26 novembre 2010
  • Intermediate pre-examination (BCM): December 3
    

    (reserved to I-Care BMC students that have participated to all activities)
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    Esempio di domande per esonero File

• 22 November - 28 November
  Genomes, genome-wide DNA and RNA analysis by microarrays and deep-sequencing methods.

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    21_lecture 22/11/2010 Folder
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    22_lecture 24/11/2010 Folder
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    23_lecture 26/11/10 Folder
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    Task BMG01 - Explore genomes and answer Quiz
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    Task BMG02: nucleotide sequence in database Assignment
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    Task BMG03 - Identificazione delle parti di una sequenza genica Assignment
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    Task BMG04 - Choose a microarray for your experiment Assignment
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    Task BMG05 - Choose a beadarray for your experiment Assignment

• 29 November - 5 December
  Transcriptome, transcription, promoters. Noncoding RNAs.
  

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    24_lecture 29/11/10 Folder
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    25_lecture 01/12/2010 Folder
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    26_lecture 03/12/2010 Folder
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    Task BMG06: how to verify bioinformatic results Assignment
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    Task BMG07: find the right protocol to RNA-Seq your samples Assignment
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    Task BMG08: what about maths? Quiz
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    Task BMG9: micro RNA specificity Assignment

• 6 December - 12 December
  Alternative splicing.
  Chromatin structure and epigenetic changes to histones and DNA.
  

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    27_lecture 06/12/2010 Folder
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    28_lecture_10/12/2010 Folder
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    Task BMG10 - Stop codons and mutations Assignment
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    Task BMG11 - what can we conclude ? Assignment

• 13 December - 19 December
  Silencing: actors and rules. Genomic imprinting. Chromatin dynamics.
  

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    29_lecture 13/12/10 Folder
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    30_lecture 15/12/10 Folder
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    31_lecture 17/12/10 Folder

• 20 December - 26 December
  Regulator elements and transcriptional control

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    32_lecture 20/12/10 Folder
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    33_lecture 21/12/2010 Folder
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    34_lecture 14/12/10 Folder
  • ATTENZIONE FILE AUDIO - Per cortesia, avrei bisogno di un file audio della seconda parte della lezione 14, del 22 dicembre. Qualcuno può passarmelo per metterlo in comune? Grazie e buone feste a tutti.
    
    
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    Task BMG12: problems with bisulfite conversion and deep-sequencing Assignment
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    Task BMG13 - How to resolve an interaction dilemma? Assignment

• 27 December - 2 January

  Not available

• 3 January - 9 January

  Not available

• 10 January - 16 January
  Alternative splicing regulation, nuclear-cytoplasmatic transports and localization.

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    35_lecture 10/01/11 Folder
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    36_lecture 12/01/11 Folder
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    37_lecture 14/01/11 Processing, export and localization Folder
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    Task BMG 14 - A method to study RNA-binding protein targets Assignment
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    Task BMG-15 A lesson-problem with mRNA localization

• 17 January - 23 January
  Post-transcriptional regulation. Mechanisms to control mRNA turnover.

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    38_lecture 17/01/11 - mRNA degradation Folder
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    39_lecture 19/01/11 - miRNA regulation and circuitry Folder
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    40_lecture 21/01/11 - Complementary lecture Folder
  • The Audio files of the last lecture are now available.
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    Appello 27 febbraio 2012 - Gambarotta URL

• 24 January - 30 January

  Not available